What is naloxone?
Naloxone, available as an easy-to-use nasal spray, can reverse an opioid overdose in minutes. It’s also known by the brand names Narcan and Kloxxado.
Naloxone temporarily blocks the effects of opioids, like fentanyl, in the body. Even if you and your friends don’t use drugs, consider carrying naloxone. You could save someone’s life.
Where to get naloxone
Naloxone is available without a prescription in all 50 states. Here are some ways you can find it near you:
- Ask a pharmacist how to get naloxone.
- Look for resources from your local health department.
- Use the map at HarmReduction.org or select your location on the Next Distro website.
How to use naloxone: 3 simple steps

If someone is showing signs of an overdose, don't wait. Call 911 and give them naloxone.
- Peel open the container.
- Place the nozzle into the person's nostril.
- Press the plunger to release the dose.
Note, it will reverse a fentanyl overdose, but because fentanyl is so strong, you may need more than one naloxone dose.
Naloxone Facts
- If you overdose, you won’t be able to use naloxone on yourself. Make sure your friends know how to use it, too.
- Each device holds one dose.
- If someone doesn't have opioids in their system, naloxone will not harm anyone who uses it.
- Even expired naloxone can save a life. (Source: NEXTDistro)