How to use naloxone

Naloxone is a safe, legal medication that can reverse an opioid overdose. Learn how to use it, and carry it with you.

What is naloxone?
  • Naloxone, available as an easy-to-use medication, can reverse an opioid overdose in minutes. It’s also known by the brand names Narcan, Kloxxado and Zimhi. 
  • Naloxone temporarily blocks the effects of opioids, like fentanyl, in the body. Even if you and your friends don’t use drugs, consider carrying naloxone. You could save someone’s life.

Where to get naloxone

Naloxone is available without a prescription in all 50 states. Here are some ways you can find it near you:

How to use naloxone nasal spray: 3 simple steps

If someone is showing signs of an overdose, don't wait. Call 911 and give them naloxone.

  1. Peel open the container.
  2. Place the nozzle into the person's nostril.
  3. Press the plunger to release the dose.

Note, it will reverse a fentanyl overdose, but because fentanyl is so strong, you may need more than one naloxone dose.

Other forms of Naloxone 
naloxone syringe

  • In addition to a nasal spray, naloxone is also available as an injectable. All versions of naloxone are safe, effective and can help save a life. 
  • Always refer to the instructions that are on the packaging for how to use naloxone. 

Naloxone facts
  • If you overdose, you won’t be able to use naloxone on yourself. Make sure your friends know how to use it, too.
  • Each device holds one dose.
  • If someone doesn't have opioids in their system, naloxone will not harm anyone who uses it.
  • Even expired naloxone can save a life. (Source: NEXTDistro
  • Training and carrying requirements for the use of naloxone do vary by state. Check out resources from your state and local health department or your school district to learn more.